Physical limitations will vary depending on the individual patient and the surgical treatment strategy that was followed. Fatigue and/or breathlessness during exercise (dyspnea) may be experienced, and arrhythmias or other symptoms may develop that will restrict forms and degrees of exertion. As with other cardiac diseases, testing will be necessary to determine safe levels of exercise for the patient with pulmonary atresia.

Anyone with congenital heart disease, repaired or non-repaired, should consult with their cardiologist about physical activity to review the risks.